|Drawn Together Character|
|Full Name||Lois Patrice Griffin|
|Religion||Jewish (formerly Protestant)|
|Voiced by||Alex Borstein|
Lois and Peter both made brief appearances in the episode The Lemon-AIDS Walk. They were seen walking past Wooldoor who was homeless and living on the streets. Peter dropped a coin in Wooldoor's cup of lemonade and Lois retorted to him, "Why'd you give him money? You know he's just going to spend it on lemonade." She was voiced by her original voice actress, Alex Borstein, when she said this.
Lois is a woman with short, neck length, orange hair that is very bright and matching to the shape of her slightly triangular hear. She has a thin, pointy nose, that is also triangular too. She has round eyes and red lips. She wears a green, buttoned shirt, tan pants, purple shoes, and blue pearl earrings.
Lois is generally, a nagging, suffering housewife with a lot of repressed anger that she holds toward Peter. Although she really is annoyed by his antics, she rarely ever does anything to express her anger, aside from making a few comments about how ridiculous it is, only to be immediately ignored. Though initially appearing to be a typical doting house wife and ideal mother, Lois has many dark aspects to her and in some cases be worse than her husband, except without the excuse of mild retardation.
- Lois, along Peter Lois never show their faces when they appear in the series. This is possibly to avoid getting a copyright claim. This same thing is also done whenever Drawn Together cameos The Simpsons.
- Lois is one of the few cameoed character in Drawn Together to be voiced by their original voice actors.